ObjectiveTo compare short-term efficacy and safety of micro channel and standard channel percutaneous nephrolithotomy holmium laser lithotripsy in treatment of complex multiple renal calculi. MethodsA total of 180 cases with complex multiple renal calculi were randomly divided into observation group and control group, 90 cases in each group. The observation group were given F16-F18 percutaneous nephroscope holmium laser lithotripsy treatment, and the control group were given F20-F24 percutaneous nephroscope holmium laser lithotripsy treatment. The therapeutic effect of the two groups were compared after treatment. ResultsThe operation time of observation group was significantly longer than that of control group, the amount of bleeding during operation was significantly less than that of the control group, the difference was statistically significant (P＜0.05); The stone free rate of the two groups was not statistically significant (P＞0.05). The complication rate of observation group was significantly higher than that of the control group, the difference was statistically significant (P＜0.05). ConclusionBoth micro channel and standard channel percutaneous nephrolithotomy holmium laser lithotripsy can obtain rather good effect in the treatment of patients with complex multiple renal calculi, and each channel has its advantages. In order to achieve a better therapeutic effect and safety of operation, we should choose the suitable size of percutaneous renal channel, according to the stone size and distribution range.

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