ObjectiveDynamic observation of peripheral progesterone levels in pregnant women at different gestational weeks in early pregnancy, and to evaluate their prediction effect of pregnancy outcome. MethodA prospective study of 3901 women in early pregnancy,dynamic monitoring of progesterone in peripheral blood was carried out in 4 to 15 weeks pregnant women with the consent of the patients,randomly,and analysis of the fluctuation of progesterone levels in peripheral blood between different gestational periods;SPSS 18 software was carried out to analyze the progesterone range of peripheral blood in different gestational weeks, and to evaluate the predictive ability of progesterone levels in peripheral blood of different gestational weeks to pregnancy outcome. ResultThe progesterone levels in peripheral blood of early pregnant women increased slowly with the increase of gestational weeks, the average weekly value is about 2 ng/mL, and has no significant relationship with gestational age, but the value between 7 to 9 weeks was less than 1.3 ng/mL. ConclusionThe progesterone levels in peripheral blood of pregnant women at different gestational weeks are closely related to pregnancy. It is relatively stable and should be closely observed. It is an important indicator to predict the outcome of pregnancy.

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