ObjectiveTo investigate clinical efficacy of comprehensive interventional therapy in treatment of hepatocellular carcinoma with hepatic dysfunction. MethodsA total of 90 cases of hepatocellular carcinoma patients with hepatic dysfunction were divided into study group and control group, 45 cases in each group. The control group was treated with hepatic arterial chemoembolization, and the patients of study group were treated by hepatic arterial segmental chemoembolization and sequential ablation combined intervention.The clinical efficacy, complications and survival rate of 6 months, 1 years and 3 years after treatment were compared. ResultsThe total effective rate of the study group (75.56%) was significantly higher than that of the control group (53.33%) (P＜0.05). The incidence of complications in the study group (6.67%) was lower than that of the control group (22.22%),the difference was statistically significant (P＜0.05). The survival rates of the study group were significantly higher than those in the control group at 6 months, 1 year and 3 year after treatment(P＜0.05). ConclusionThe clinical efficacy of comprehensive interventional therapy in treatment of hepatocellular carcinoma with hepatic dysfunction is significant, and the incidence of complications is low, the survival rate is high.

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