ObjectiveTo explore the clinical efficacy of CT guided laser ablation combined with collagenase injection and Huoxueshujin prescription in the treatment of lumbar disc herniation. MethodsA total of 180 cases with lumbar disc herniation were divided into control group and observation group, 90 cases in each group.Patients of control group were treated with ablation and collagenase guided by CT;patients of observation group were treated with Huoxueshujin prescription on the basis of control group. After treatment, the clinical efficacy of the two groups were compared. ResultsThe patients of observation group received excellent effects in 43 cases, good in 35 cases, median in 8 cases, poor in 4 cases; The patients of control group received excellent effects in 15 cases, good in 42 cases, median in 21 cases, poor in 12 cases; The effect of observation group was better than that of control group, the difference was statistically significant(P＜0.05). After treatment, the activities, self care, daily activities, pain/discomfort, anxiety/depression scores of observation group were lower than that of control group, the differences were statistically significant(P＜0.05). After treatment, the protrusions of observation group showed by CT imaging decreasedmore than that of control group, the difference was statistically significant(P＜0.05). The swelling rate of observation group was 2.2% (2/90), lower than 10.0% (9/90) of control group, the difference was statistically significant (P＜0.05).The incidence rate of discomfort/tenderness in observation group was 5.6% (5/90), and 10.0%(9/90) in control group, the difference was not statistically significant (P＞0.05). The incidence rate of adverse reactions in observation group was 7.8% (7/90), and 15.6% (14/90) in control group, the difference was not statistically significant (P＞0.05). ConclusionsCT guided laser ablation combined with collagenase injection and Huoxueshujin prescription could obtain obvious clinical effect in the treatment of lumbar disc herniation.

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