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目的探讨经皮冠状动脉介入术（PCI）在急性冠脉综合征（ACS）合并慢性肾脏病（CKD）患者中的临床效果与安全性。方法选择接受PCI治疗的ACS合并CKD患者165例为PCI组，另选择一般资料与PCI组患者相匹配的ACS合并CKD患者165例为保守组。保守组采用包括噻氯匹啶 、阿司匹林、他汀类等药物治疗。PCI组在常规药物治疗基础上接受PCI手术治疗。评价两种疗法的有效性与安全性。结果PCI组院内死亡率、住院期间肾功能恶化率、出院后死亡率等指标显著低于保守组，两组比较，差异有统计学意义（P＜0.05）。结论PCI治疗对ACS合并CKD患者，有降低其院内死亡率的趋势，无增加院内肾功能恶化的风险。
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临床研究
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更新时间：2016-01-12
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经皮冠状动脉介入术在急性冠脉综合征合并慢性肾脏病患者中的应用研究
The effectiveness and safety of percutaneous coronary intervention in patients with acute coronary syndromes and chronic kidney disease
微创医学 201506期 页码：773-775
作者机构：江西省上饶卫生学校潘阳分校，上饶市333100
基金信息：者简介：曹小川（1975～），女，本科，副主任医师，研究方向：临床内科。
- 中文简介
- 英文简介
- 参考文献
ObjectiveTo explore the clinical effect and safety of percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS) complicated with chronic kidney disease (CKD). MethodsA total of 165 patients with ACS complicated CKD, which were treated by PCI, were selected as PCI group. Another 165 patients with ACS complicated with CKD, whose general information were matched the PCI group,were selected as conservative treatment group. The effectiveness and safety of the two therapies were compared after treatment. ResultsThe mortality rate, deterioration rate of renal function, and the mortality rate after discharge of PCI group were significantly lower than that of the conservative group, the difference was statistically significant (P＜0.05). ConclusionsPCI can effectively reduce the risk of hospital mortality in patients with ACS complicated with CKD, but not increase the risk of deterioration of renal function.
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