ObjectiveTo compare clinical effect of single segment cervical artificial intervertebral disc（Mobi-C） replacement and anterior cervical fusion in treatment of cervical disc herniation, and verify the long-term efficacy of verification of Mobi-C disc replacement. MethodsA total of 126 cases with single segmental cervical intervertebral disc herniation were randomly divided into observation group (64 cases) and control group (62 cases). The observation group was treated with Mobi-C disc replacement, the control group were treated with anterior cervical fusion. The two groups were followed up for more than 5 years. Responsible for clearance activity, reoperation rate, cervical JOA score, VAS score and NDI score were compared between the two groups. ResultsFinally, 56 cases in the observation group, 55 cases in the control group were followed up at least 5 years. The responsible for clearance activity of the observation group was significantly greater than that of the control group (P＜0.001). The reoperation rate of observation group was significantly lower than the control group (P＜0.02). Comparison of two groups of JOA score and VAS score, the difference was not statistically significant(P＞0.05). ConclusionMobi-C surgery and ACDF surgery were both effective in treatment of cervical intervertebral disc herniation. Differently, the ROM of the treated segment were relatively better preserved in the Mobi-C surgery than ACDF surgery. Subsequently, incidence of adjacent segment degeneration and re-operation was lower significantly in Mobi-C group compared with ACDF group. Mobi-C surgery was safe enough as an encouraging safe alternative to ACDF surgery.

• ref