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目的探讨丹参预防内镜逆行胰胆管造影（ERCP）术后高淀粉酶血症及胰腺炎的疗效。方法选择胆石症行ERCP术患者31例，ERCP术后常规给予常规鼻胆引流、抗感染、抑制胰酶分泌等治疗；于ERCP术前及术后1 d，予丹参注射液250 mL，每日2次静点。分别于术前、术后3 h、24 h抽血，检测血淀粉酶、脂肪酶水平、24 h C反应蛋白（CRP）。结果发生高淀粉酶血症10例，无胰腺炎发生。结论丹参对ERCP术后预防高淀粉酶及胰腺炎有一定的临床价值。
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更新时间：2015-03-30
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丹参预防ERCP术后高淀粉酶血症及胰腺炎的临床疗效观察▲
Clinical investigation of Tanshinone in preventing hyperamylasemia and pancreatitis following endoscopic retrograde cholangiopancreatography
微创医学 201403期 页码：284-286
作者机构：(广西钦州市第一人民医院消化二科,钦州市535000)
基金信息：（广西钦州市第一人民医院消化二科，钦州市535000）▲基金项目：广西卫生厅科研项目（合同号：Z2013749）▲基金项目：广西卫生厅科研项目（合同号：Z2013749）作者简介：韦良宏（1973～），男，硕士研究生，主任医师，
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ObjectiveTo observe the clinical effects of Tanshinone in preventing hyperamylasemia and pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP). MethodsThirtyone cholelithiasis patients routinely received, antibiotics, and pancreatin depressing after ERCP, as well as intravenous injection of Tanshinone(a dose of 250ml, twice a day right before ERCP and 1 day after ERCP). The level of serum amylase and lipase at right before ERCP, 3 h after, and 24h after ERCP, and CRP at 24h after ERCP were measured. ResultsTen cases of hyperamylasemia happened, but no pancreatitis occurred. ConclusionTanshinone has certain clinical value in preventing hyperamylasemia and pancreatitis following ERCP.
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