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超声消融治疗多发性子宫肌瘤的影响因素研究▲
Investigation on influence factors of ultrasound ablation in treating multiple uterine fibroids

微创医学 201403期 页码:260-262

作者机构:(1 重庆医科大学生物医学工程学院,省部共建超声医学工程国家重点实验室培育基地,超声医学工程重庆市重点实验室,重庆市400016;2 重庆海扶医疗科技股份限公司,重庆市400016)

基金信息:▲基金项目:“十二五”国家科技支撑计划(No.2011BAI14B01);2011年高等学校博士学科点专向科研基金联合资助课题(20115503110014)。

DOI:10.11864/j.issn.1673.2014.03.02

  • 中文简介
  • 英文简介
  • 参考文献
目的探讨影响超声消融治疗多发性子宫肌瘤的因素。方法对32例多发性子宫肌瘤患者进行一次性超声消融治疗,同时记录患者术中不良反应。术前及术后第2天所有患者均行盆腔MRI平扫+增强检查,计算不同肌瘤大小、位置、类型的肌瘤消融率。结果①32例多发性子宫肌瘤患者均顺利完成超声消融治疗,术中均发生不适反应,但无需治疗,无不良后果。②肌瘤消融情况分析:消融前MRI检查显示32例患者最大径≥10 mm肌瘤共132个,术后增强MRI显示其中91个肌瘤完全或大部分无强化。不同肌瘤类型及位置与肌瘤消融率差异无统计学意义(P>0.05),不同肌瘤大小的肌瘤消融率不同(P<0.05)。结论超声消融治疗多发性子宫肌瘤是一种安全、有效的无创方法,影响多发性子宫肌瘤能否完全消融的主要因素是肌瘤的大小。
ObjectiveTo Investigate influence factors of ultrasound ablation in treating multiple uterine fibroids. MethodsThirtytwo patients of multiple uterine fibroids were underwent high intensity focused ultrasound ablation (USgHIFU) in one session, and their discomforts during the treatment were recorded. All the patients were performed with pelvic dynamic MRI before and 2 days after ablation, and the ablation rates of uterine fibroid of different sizes, locations, and types were calculated. ResultsThirtytwo patients of multiple uterine fibroids completed the USgHIFU ablation treatment. All patients complained discomfort that didn’t need to be dealt with. The pelvic MRI before ablation showed 132 uterine fibroids altogether with a diameter of more than 10 cm, of which, 92 showed no enhancement or little enhancement after ablation. There was statistical significant difference in ablation rate among groups of different fibroids sizes, but not among groups of different fibroid types or locations. ConclusionThe USgHIFU ablation treatment for multiple uterine fibroids is safe and effective, and its main efficacy factor might be the size of uterine fibroids.
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