Objective To evaluate the efficacy of partial salpingectomy by laparoscopic endoloop ligation combined with pituitrin in interstitial tubal pregnancy. Methods1 35 patients with interstitial tubal pregnancy were divided into study group (n=68) and control group (n=67) depending on whether the lesion was injected with pituitrin before operation. In the study group, the junction of normal myometrium and the lesion was transabdominally injected with pituitrin 6 U under laparoscopyguided, and then the isthmus of fallopian tube was coagulated and divided. The mesosalpinx and vessels were dissected, which was not beyond the uterine horn. The fundus of the mass was ligated with an endoloop after removal of the lesion. Partially resection was performed in the fallopian tube 0.5cm above the knot. The uterine horn was injected with methotrexate 25mg for prevention from persistent ectopic pregnancy. The patients in the control group underwent the operation without pituitrin injection. Operative duration, intraoperative blood loss, postoperative HCG clearance time and the incidence of persistent ectopic pregnancy were assessed in two groups. Results The operative duration, intraoperative blood loss, postoperative HCG clearance time were shorter, and the incidence of persistent ectopic pregnancy was lower in the study group compared to the control group, which had a statistically difference.The blood pressure after anesthesia had a difference from that at 10 min and 20 min after pituitrin administration (P＜0.05), but had no difference from that at 30 min after pituitrin administration (P＞0.05). Conclusions The partial salpingectomy by pituitrin combined with laparoscopic ligation with endoloops is a safe and easy approach for interstitial tubal pregnancy.

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