Objective To evaluate the clinical efficacy of retroperitoneal laparoscopic nephron sparing surgery for kidney neoplasm. Methods 30 patients with kidney neoplasm underwent retroperitoneal laparoscopic nephron sparing surgery. And there were 16 cases with right kidney neoplasm, 14 cases with left kidney neoplasm. Results The laparoscopic nephron sparing surgery was completed successfully in 28 cases. One case had difficulty with suture under laparoscopy and was converted to open surgery due to the special location of the tumor. And one case was converted to laparoscopic radical nephrectomy because the renal collection system was invaded by the tumor. The mean operative duration was 154 min ［range, (60-345) min］. The mean warm ischemia time was 26 min ［range, (20-50) min］. The mean estimated blood loss was 0.104 L ［range, (0.030-0.400)L］. Perioperative transfusion was not conducted in any of cases. No postoperative complications of hemorrhage and urinary leakage occurred. Pathologic results revealed negative surgical margins in all cases. The mean hospital stay after the surgery was 9.6 d ［range, (5-17) d］. There were no tumor recurrences during the followedup of 10 to 26 months. Conclusions Retroperitoneal laparoscopic nephron sparing surgery has various advantages for earlystage kidney neoplasm including clear operative field, faster recovery, less complication and less tissue trauma. And it is worthy of application and promotion in qualified hospitals.

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