Objective To explore the difference of sinonasal mucosa outcomes in different age groups of patients with chronic bilateral rhinosinusitis with nasal polyps after functional endoscopic nasal surgery. Methods 84 patients diagnosed as chronic bilateral rhinosinusitis with nasal polyps were divided into adolescent group(n=20), adult group(n=48) and elderly group(n=16).All of cases were assessed in bilateral lesions using Lund-Kennedy endoscopic scoring system in the first week, first month, third month, sixth month and 12th month after surgery. Comparison about endoscopic appearances scores and epithelialization proportion of sinonasal mucosa was performed in three groups. Results There was no difference about the endoscopic appearances scores in three groups in the first week after surgery（F=0.81,P＞0.05）. And the scores in adolescent group were higher than in the adult group or the elderly group in first and third month after surgery (P＜0.05). The scores of the sixth month and 12th month after surgery had no difference in three groups (F=1.4, P＞0.05). The epithelialization proportions one year after surgery in the adolescent group, the adult group and the elderly group were 50%、75%、87.5%, respectively(χ2=6.72,P＜0.05). The epithelialization proportion in the adolescent group was lower than in the adult group or the elderly group. Conclusions The outcomes of sinonasal mucosa mucosa in patients with chronic rhinosinusitis with nasal polypus after functional endoscopic nasal surgery differ significantly in different age groups. The epithelialization proportion in the adolescent patients was lower than in the adult or elderly patients one year after surgery.

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