Objective To evaluate the value and safety of entiretransurethral enucleation combined with morcellation of the gland via assisted suprapubical small channel for giant prostatic hyperplasia. Methods The volume of the prostate of 23 patients suffered benign prostatic hyperplasia were more than 150 ml preoperative,ranging frome 153 to 263 ml, averaging 176±22ml. All of them were treated by entire transurethral enucleation combined with morcellation of the gland via suprapubical small channel. The data of hemoglobin, function of kidney, electrolyte, blood gas analysis before and after the operation were compared. Transfusion, TRU syndrome or deep venous thrombosis were also analyzed. Results All patients were successfully treated, The time of operation was 86～126 min, with the average of 97±13 min. The mean weight of resected gland was 118±15g, ranging from 87 g to 168 g. The value of hemoglobin, Na+, BE decreased, and PaO2 were all significantly increased (P＜0.05). BUN,Cr, K+,Cl-,Ph and PaCO2 showed no differences(P＞0.05). TRU syndrome occurred in one case. Neither transfusion nor deep venous thrombosis occurred. No acute urinary retention happened after catheter was removed. Conclusions It is safe and practical to undergo transurethral enucleation combined with morcellation of the gland via assisted suprapubical small channel for giant prostatic hyperplasia. It is a new way of operation for giant prostatic hyperplasia.

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