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目的探讨经导管肝动脉化疗栓塞(TACE)联合经皮微波消融(PMCT)治疗肝细胞癌的临床疗效和安全性。方法将82例肝癌患者分为联合组(TACE+PMCT)45例,对照组(单纯TACE)37例,随访1～2年,对比两组治疗效果和不良反应。结果联合组肿瘤完全坏死和AFP水平下降>50%的患者均高于对照组,差异有统计学意义(P<0.05);联合组的1年、2年生存率均比对照组高,1年、2年复发率比对照组低,两组均未发生严重不良反应。结论 TACE+PMCT治疗直径>3cm的肝细胞癌疗效确切,安全可行。
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更新时间：2015-07-03
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肝动脉化疗栓塞联合微波消融治疗肝细胞癌的研究
Combination of transcatheter arterial chemo-embolization and percutaneous microwave coagulation therapy in the treatment of hepatocellular carcinoma
微创医学 201004期 页码：333-335
作者机构： 广西南宁市第一人民医院普外科
基金信息：
- 中文简介
- 英文简介
- 参考文献
Objective To investigate the efficacy and safety of combination of transcatheter arterial chemo-embolization (TACE) and percutaneous microwave coagulation therapy (PMCT) in treatment of hepatocellular carcinoma (PHC).Methods 82 cases of PHC were divided into combined group (TACE+PMCT,n=45) and control group (only TACE,n=37).Patients were followed up for 1 to 2 years,and the therapeutic effects and side effects were compared between the two groups.Results The patients with tumor completely necrosis and AFP level lower than >50% in combined group were significantly more than those in control group (P<0.05);the one year and two years survival rate in combined group were greatly higher than those of control group,and the recurrence rate was lower than control group;no severe side effect was observed in two groups.Conclusion TACE+PMCT is effective and safe in treatment of PHC of more than 3 cm in diameter.
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