Objective To investigate the clinical efficacy of arthroscopic treatment of children's tibial intercondylar crest fracture by using PDS-Ⅱ line combined with Endobutton steel plate fixation through a single tunnel with evasive epiphyseal plate. Methods The clinical data of 11 children with tibial intercondylar crest fracture were analyzed retrospectively. All of the children underwent arthroscopic treatment by using PDS-Ⅱ line combined with Endobutton steel plate through a single tunnel with evasive epiphyseal plate. Postoperative follow-up was conducted to observe the fracture healing and the stability of knee joint, and to record the Lysholm score of knee joint, the score of Functional Independence Measure (FIM), the subjective score of knee joint of 2000 International Knee Documentation Committee (2000 IKDC), the pain Visual Analogue Scale (VAS) score, the occurrence of complications and the recovery of knee joint function. Results Eleven patients were followed up for 6 to 12 months, with an average of 9.4 months. (1) On the first day after operation, the X-ray reexamination of the injured knee showed that the avulsion bone of tibial intercondylar crest was restored satisfactorily, and all the incisions were healed and sutured within 2 weeks. All patients had bone healing at 3 months after operation, without fracture malunion, limb length discrepancy, varus or valgus deformity of the injured limb. The knee joint activity was normal, the anterior drawer test and Lachman test were negative, and the knee joint stability was good. (2) The Lysholm score, 2000 IKDC score and FIM scale score increased and the pain VAS score decreased successively before operation, 2 weeks after operation, 3 months after operation and the last follow-up. At the last follow-up, the Lysholm score of knee joint basically recovered to the pre-injury level, the 2000 IKDC subjective knee score basically reached full score, and most patients were in a painless state. (3) At 6 months after operation, the excellent and good rate of knee joint was 100.00%. All patients had no postoperative complications such as inconsistent length of lower limbs, inconsistent valgus angle of bilateral knee joints, incision infection, and internal fixation displacement. Conclusion Arthroscopic treatment of children's tibial intercondylar crest fracture by using PDS-Ⅱ line combined with Endobutton steel plate through a single tunnel with evasive epiphyseal plate is a minimally invasive and reliable treatment method, which is simple in operation, reliable in fixation, good in treatment effect, and can avoid epiphyseal plate injury and other related complications.