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CT引导下冷循环射频消融联合肝动脉热化疗栓塞治疗中晚期原发性肝癌
Combination of CT.·guided coo1.-tip radiofrequency ablation with thermochem oemboliza· tion in treating advanced primary hepatoccllular carcinoma

微创医学 201003期 页码:202-204

作者机构: 安徽省淮南市淮南东方医院集团肿瘤医院肿瘤科; 安徽淮南市东方医院集团合福医院放射科

基金信息: 收稿日期:2010-03—1

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目的探讨CT引导下冷循环射频消融联合肝动脉热化疗栓塞治疗中晚期原发性肝癌的疗效。方法 65例中、晚期原发性肝癌患者按单双日法分为冷循环射频消融联合肝动脉热化疗栓塞组(联合治疗组,A组)31例,单纯肝动脉热化疗栓塞组(单纯组,B组)34例,治疗后通过CT、DSA及血清甲胎蛋白(AFP)测定评价。结果单纯肝动脉热化疗栓塞组(B组)的肿瘤完全坏死率、初次复发率及1年生存率分别为17.6%、38.2%、47.1%,而联合治疗组分别为48.4%、9.7%、80.6%,差异均有统计学意义。结论 CT引导下冷循环射频消融治疗联合肝动脉热化疗栓塞较单纯肝动脉热化疗栓塞治疗中、晚期肝癌效果好。
Objective To investigate the therapeutic efect of cT—guide cool-tip radiofrenquency ablation(RFA) combined with On in treating advanced primary hepatoeellular carcinoma.Methods 65 cases of ad— vanced primary hepatocellular carcinoma were randomly divided into two groups:31 cases were treated with RFA and thermochemoembolization( combination group,or Group A)and 34 case were treated with thermochemoembolization only (Group B).The evaluation of therapeutic efects was carried out through digital subtraction angiography(DSA),CT and sertim AFP.Results Th e complete necrosis mte of tumor,the recurrence rate,and one--year survival rate were 17.6% , 38.2% ,47.1% in group B,and48.4% ,9.7% ,80.6% in Group A,respectively(all with statistical significant diference). Conclusion Th e therapeutic efects of thermochemoembolization combined with cool—tip RFA show better results than that on alone in treating the moderate and advanced stage primary hepatoeelluation carcinoma
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