微创医学

目的观察异丙酚联合适当剂量的芬太尼和阿托品静脉麻醉在人工流产手术中的作用。方法选择自愿接受人工流产的早孕妇女200例,随机分为A、B两组,每组100例,A组单纯使用异丙酚静注,B组使用异丙酚联合芬太尼、阿托品静注。观察两组患者诱导时间、苏醒状况、离院时间、手术时间、异丙酚用量、两组病人的麻醉效果;记录诱导前及诱导后平均动脉压(MAP)、心率(HR)、呼吸频率(RR)、脉搏氧饱和度(SpO2)的变化和两组病人的不良反应。结果 B组的麻醉起效时间、异丙酚用量、不良反应均少于A组,麻醉镇痛效果优于A组,差异有统计学意义。苏醒时间、平均手术时间两组间差异无显著性。两组诱导后平均动脉压(MAP)、心率(HR)、呼吸频率(RR)、脉搏氧饱和度(SpO2)均有小幅度降低,但很快自行恢复。结论异丙酚联合应用适当剂量的芬太尼和阿托品用于人工流产手术的麻醉效果确切,安全可靠。

Objective To observe effects of proper dose of propofol combined with fentanyl and atropine on artificial abortion.Methods 200 cases of voluntary abortion women in early pregnancy were randomly divided into 2 groups,100 cases in each group:group A,propofol alone,and group B,propofol combined with fentanyl and atropine,all intravenously.Induction time,recovery status,discharge time,operation time,dosage of propofol,anesthesia effects,and mean arterial pressure(MAP),heart rate(HR),respiratory rate(RR),pulse oxygen saturation(SpO2) changes and adverse reactions in two groups were compared.Results The onset time of anesthesia,propofol dosage,adverse reactions were less in group B than in group A,and the narcotic analgesia was better in group B,all with statistical significance.There was no significant difference in recovery time and mean operative time between the two groups.MAP after induction,HR,RR,SpO2 were slightly declined in both groups,but soon resumed.Conclusion The anesthetic effect of propofol combined with appropriate doses of fentanyl and atropine for induced abortion is precise,safe and reliable.

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