目的评价早期应用半导体激光周边虹膜成形术治疗原发性闭角型青光眼急性发作的安全性和有效性。方法对2007年4月至2010年11月确诊的原发性闭角型青光眼急性发作患者50例58眼随机分为治疗组和对照组,对照组应用降眼压药物治疗,治疗组采用半导体激光周边虹膜成形术治疗,观察眼压变化、房角开放情况、视力恢复情况及治疗组术后并发症。结果眼压:两组眼压治疗后均比治疗前有所下降,治疗组下降幅度明显高于对照组(P〈0.05)。房角开放情况:两组功能关闭的房角均有不同程度重新开放,治疗后24 h前房角开放范围〉1/2周者,对照组9眼(32.14%),治疗组26眼(86.67%),两组比较有显著性差异(P〈0.05)。视力改善情况:治疗后24 h对照组视力变化不明显,治疗组视力0.08~0.4,较术前眼前手动-0.2明显提高。所有病例均无严重并发症。结论半导体激光周边虹膜成形术可使功能关闭的房角迅速开放,眼压下降,视力恢复快,并发症少,是治疗原发性闭角型青光眼急性发作的一种安全有效的方法。
Objective To evaluate the safety and effectiveness of semiconductor laser peripheral iridoplasty for the early treatment of acute attack of primary angle-closure glaucoma.Methods 58 eyes of 50 patients diagnosed with primary acute angle-closure glaucoma From April 2007 to November 2010 were randomly divided into treatment and control groups.The control group was treated with hypotensive drug,and the treatment group was treated with semiconductor laser peripheral iridoplasty.Intraocular pressure change,open angle,and visual acuity recovery of both groups,and postoperative complications of the treatment group were observed.Results Intraocular pressure decreased after treatment in both groups,but the argument were much more apparent in the treatment group than that in the control group(P0.05).Functionally closed chamber angle reopened in different degrees in both groups.The reopen content was more than 1/2 24h after operation in 9 cases(32.14%)in the control group,and in 26 cases(86.67%)in the treatment group,showing a statistically significant difference between the two groups(P0.05).Visual acuity did not changed in the control group,while it increased from acuity motion-0.2 before operation to 0.08~0.4 in the treatment group 24h after treatment.Conclusion Semiconductor laser peripheral iridoplasty can quickly make the function angle closure reopened,intraocular pressure decreased,the visual acuity recovered and with less complications,indicating it as a safe and effective method in the treatment of acute attacks of primary closed angle glaucoma.